Ontology highlight
ABSTRACT:
SUBMITTER: Liu DZ
PROVIDER: S-EPMC2949089 | biostudies-other | 2010 Jan
REPOSITORIES: biostudies-other
Liu Da-Zhi DZ Tian Yingfang Y Ander Bradley P BP Xu Huichun H Stamova Boryana S BS Zhan Xinhua X Turner Renee J RJ Jickling Glen G Sharp Frank R FR
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090902 1
MicroRNAs (miRNAs) regulate gene expression and have a critical role in many biologic and pathologic processes. We hypothesized that miRNA expression profiles in injured brain (hippocampus) would show common as well as unique profiles when compared with those of blood. Adult, untouched, control rats were compared with rats with sham surgeries, ischemic strokes, brain hemorrhage (lysed blood, fresh blood, or thrombin), and kainate-induced seizures. Brain and whole-blood miRNA expression profiles ...[more]