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(Z)-Ethyl 3-(4-chloro-phen-yl)-2-cyano-3-(2,6-difluoro-benzamido)acrylate.

ABSTRACT: The title compound, C(19)H(13)ClF(2)N(2)O(3), was prepared by the reaction of (Z)-ethyl 3-amino-3-(4-chloro-phen-yl)-2-cyano-acrylate and 2,6-difluoro-benzoyl chloride. The dihedral angle between the chloro-benzene and fluoro-benzene rings is 37.0?(1)°. The ethyl group is disordered over two positions [occupancies = 0.52?(2):0.48?(2)]. In addition to intra-molecular N-H?O and N-H?F hydrogen bonds, the crystal packing shows the mol-ecules to be connected by inter-molecular C-H?O and C-H?N hydrogen bonds.

SUBMITTER: Dehua Z

PROVIDER: S-EPMC2959890 | biostudies-other | 2008

REPOSITORIES: biostudies-other

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(Z)-Ethyl 3-(4-chloro-phen-yl)-2-cyano-3-(2,6-difluoro-benzamido)acrylate.

Dehua Zhang Z Xiaoyan Zhang Z

Acta crystallographica. Section E, Structure reports online 20081108 Pt 12

The title compound, C(19)H(13)ClF(2)N(2)O(3), was prepared by the reaction of (Z)-ethyl 3-amino-3-(4-chloro-phen-yl)-2-cyano-acrylate and 2,6-difluoro-benzoyl chloride. The dihedral angle between the chloro-benzene and fluoro-benzene rings is 37.0 (1)°. The ethyl group is disordered over two positions [occupancies = 0.52 (2):0.48 (2)]. In addition to intra-molecular N-H⋯O and N-H⋯F hydrogen bonds, the crystal packing shows the mol-ecules to be connected by inter-molecular C-H⋯O and C-H⋯N hydroge ...[more]

PMID: 21581235

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