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(Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl-ene]indolin-2-one.

ABSTRACT: The title compound, C(13)H(9)FN(2)O, a potential neuroprotective agent, consists of an indolinone and a pyrrolyl unit [dihedral angle between the ring planes = 4.9?(1)°]. An intra-molecular hydrogen bond between the carbonyl O atom and the NH group of pyrrole correlates with the Z arrangement of the substituents at the C=C bond. In the crystal, inversion dimers occur, linked by pairs of N-H?O bonds.

SUBMITTER: Zhang H

PROVIDER: S-EPMC2967860 | biostudies-other | 2008

REPOSITORIES: biostudies-other

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(Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl-ene]indolin-2-one.

Zhang Hongming H Ankati Haribabu H Akubathini Shashidhar Kumar SK Biehl Ed E

Acta crystallographica. Section E, Structure reports online 20081203 Pt 1

The title compound, C(13)H(9)FN(2)O, a potential neuroprotective agent, consists of an indolinone and a pyrrolyl unit [dihedral angle between the ring planes = 4.9 (1)°]. An intra-molecular hydrogen bond between the carbonyl O atom and the NH group of pyrrole correlates with the Z arrangement of the substituents at the C=C bond. In the crystal, inversion dimers occur, linked by pairs of N-H⋯O bonds. ...[more]

PMID: 21581718

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