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Methyl 5,6-dimeth-oxy-1H-indole-2-carboxyl-ate.

ABSTRACT: The title compound, C(12)H(13)NO(4), was prepared as a precursor to an indole derivative with possible anti-mitotic properties. The mol-ecule is very nearly planar; the maximum deviation of any non-H atom from the mean plane of the indole ring is 0.120?(3)?Å for each of two meth-oxy C atoms. The pairs of mol-ecules related by the inversion centre at (0,0,) are connected by two symmetry-equivalent N-H?O hydrogen bonds, while the pairs of mol-ecules related by the inversion centre at (0,0,0) exhibit a ?-stacking inter-action of the indole rings, with an inter-planar separation of 3.39?(3)?Å.

SUBMITTER: Monroe TB

PROVIDER: S-EPMC2970210 | biostudies-other | 2009

REPOSITORIES: biostudies-other

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Methyl 5,6-dimeth-oxy-1H-indole-2-carboxyl-ate.

Monroe Thomas Blake TB Moazami Yasamin Y Jones Daniel S DS Ogle Craig A CA

Acta crystallographica. Section E, Structure reports online 20090905 Pt 10

The title compound, C(12)H(13)NO(4), was prepared as a precursor to an indole derivative with possible anti-mitotic properties. The mol-ecule is very nearly planar; the maximum deviation of any non-H atom from the mean plane of the indole ring is 0.120 (3) Å for each of two meth-oxy C atoms. The pairs of mol-ecules related by the inversion centre at (0,0,) are connected by two symmetry-equivalent N-H⋯O hydrogen bonds, while the pairs of mol-ecules related by the inversion centre at (0,0,0) exhib ...[more]

PMID: 21577822

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