2-Iodo-3-meth-oxy-6-methyl-pyridine.

ABSTRACT: The title compound, C(7)H(8)INO, which crystallizes with three independent mol-ecules in the asymmetric unit, was prepared by the reaction of 3-meth-oxy-6-methyl-pyridine with KI and I(2) in tetra-hydro-furan solution. In the crystal structure, the three independent mol-ecules are arranged in a similar orientation with the three polar meth-oxy groups aligned on one side and the three non-polar methyl groups on the other side. The three mol-ecules, excluding methyl H atoms, are essentially planar, with r.m.s. deviations of 0.0141?(1), 0.0081?(1) and 0.0066?(2)Å. The three pyridine rings make dihedral angles of 58.09?(3) 66.64?(4) and 71.5?(3)°. The crystal structure features rather weak inter-molecular C-H?O hydrogen bonds, which link two mol-ecules into dimers, and short I?N contacts [4.046?(3)?Å].

SUBMITTER: Guo W 

PROVIDER: S-EPMC2971865 | biostudies-other | 2009

REPOSITORIES: biostudies-other