V-maf, a viral oncogene that encodes a "leucine zipper" motif.
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ABSTRACT:
SUBMITTER: Nishizawa M
PROVIDER: S-EPMC298140 | biostudies-other | 1989 Oct
REPOSITORIES: biostudies-other
Publications
v-maf, a viral oncogene that encodes a "leucine zipper" motif.
Nishizawa M M Kataoka K K Goto N N Fujiwara K T KT Kawai S S
Proceedings of the National Academy of Sciences of the United States of America 19891001 20
We have molecularly cloned the provirus of the avian musculoaponeurotic fibrosarcoma virus AS42. Nucleotide sequence analysis of a biologically active clone of AS42 showed that this virus encodes a viral oncogene, maf. The deduced amino acid sequence of the v-maf gene product contains a "leucine zipper" motif similar to that found in a number of DNA binding proteins, including the gene products of the fos, jun, and myc oncogenes. However, unlike these oncogenes, the cellular maf gene was not tra ...[more]
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