Ontology highlight
ABSTRACT:
SUBMITTER: Young D
PROVIDER: S-EPMC298198 | biostudies-other | 1989 Oct
REPOSITORIES: biostudies-other
Young D D Riggs M M Field J J Vojtek A A Broek D D Wigler M M
Proceedings of the National Academy of Sciences of the United States of America 19891001 20
We cloned the adenylyl cyclase gene from the fission yeast Schizosaccharomyces pombe using low-stringency hybridization to the Saccharomyces cerevisiae adenylyl cyclase gene. The Sc. pombe gene encodes a 1692-amino acid-residue protein. The identity of this gene was confirmed by studies of its expression in Sa. cerevisiae. Expression of the carboxyl-terminal region of the Sc. pombe adenylyl cyclase protein will suppress a temperature-sensitive mutation in the Sa. cerevisiae adenylyl cyclase gene ...[more]