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High-throughput injection with microfluidics using picoinjectors.

ABSTRACT: Adding reagents to drops is one of the most important functions in droplet-based microfluidic systems; however, a robust technique to accomplish this does not exist. Here, we introduce the picoinjector, a robust device to add controlled volumes of reagent using electro-microfluidics at kilohertz rates. It can also perform multiple injections for serial and combinatorial additions.

SUBMITTER: Abate AR 

PROVIDER: S-EPMC2984161 | biostudies-other | 2010 Nov

REPOSITORIES: biostudies-other

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High-throughput injection with microfluidics using picoinjectors.

Abate Adam R AR   Hung Tony T   Mary Pascaline P   Agresti Jeremy J JJ   Weitz David A DA  

Proceedings of the National Academy of Sciences of the United States of America 20101020 45

Adding reagents to drops is one of the most important functions in droplet-based microfluidic systems; however, a robust technique to accomplish this does not exist. Here, we introduce the picoinjector, a robust device to add controlled volumes of reagent using electro-microfluidics at kilohertz rates. It can also perform multiple injections for serial and combinatorial additions. ...[more]