Ontology highlight
ABSTRACT:
SUBMITTER: Barraud P
PROVIDER: S-EPMC3000254 | biostudies-other | 2010 Dec
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 20101115 49
Olfactory ensheathing cells (OECs) are a unique class of glial cells with exceptional translational potential because of their ability to support axon regeneration in the central nervous system. Although OECs are similar in many ways to immature and nonmyelinating Schwann cells, and can myelinate large-diameter axons indistinguishably from myelination by Schwann cells, current dogma holds that OECs arise from the olfactory epithelium. Here, using fate-mapping techniques in chicken embryos and ge ...[more]