Ontology highlight
ABSTRACT:
SUBMITTER: Butterfield AE
PROVIDER: S-EPMC3000513 | biostudies-other | 2010 Dec
REPOSITORIES: biostudies-other
Butterfield Anthony E AE Stewart Russell J RJ Schmidt Christoph F CF Skliar Mikhail M
Biophysical journal 20101201 12
Optical trapping experiments reveal details of molecular motor dynamics. In noisy data, temporal structure within the power stroke of motors can be analyzed by ensemble averaging, but this obscures infrequent subcategories of events. We have here developed an analysis method that uses Kalman filtering of measurements, model-based estimation of the power strokes produced by the motor head, and automatic event classification to discriminate between different types of motor events. This method was ...[more]