Ontology highlight
ABSTRACT:
SUBMITTER: Beckstead WA
PROVIDER: S-EPMC3001109 | biostudies-other | 2008 Oct-Dec
REPOSITORIES: biostudies-other
Mammalian genome : official journal of the International Mammalian Genome Society 20081029 10-12
Genome-wide analysis of single nucleotide polymorphism (SNP) markers is an extremely efficient means for genetic mapping of mutations or traits in mice. However, this approach often defines a relatively large recombinant interval. To facilitate the refinement of this interval, we developed the program SNP2RFLP. This program can be used to identify region-specific SNPs in which the polymorphic nucleotide creates a restriction fragment length polymorphism (RFLP) that can be readily assayed at the ...[more]