Ontology highlight
ABSTRACT:
SUBMITTER: Klipa D
PROVIDER: S-EPMC3011215 | biostudies-other | 2010 Nov-Dec
REPOSITORIES: biostudies-other
mAbs 20101101 6
The use of antibodies in transplantation dates to 1986 when muromonab CD3, a monoclonal antibody (mAb) targeting CD3, was first approved for prevention and treatment of renal allograft rejection. These agents have largely been used in a brief adjunctive manner to provide immunosuppression during the initial period after solid organ transplantation or during an episode of acute rejection. Recent advances in our understanding of transplant immunology have allowed emergence of numerous new mAbs, ta ...[more]