Ontology highlight
ABSTRACT:
SUBMITTER: Mullis PE
PROVIDER: S-EPMC3014602 | biostudies-other | 2010
REPOSITORIES: biostudies-other
Journal of clinical research in pediatric endocrinology 20100501 2
When a child is not following the normal, predicted growth curve, an evaluation for underlying illnesses and central nervous system abnormalities is required, and appropriate consideration should be given to genetic defects causing growth hormone (GH) deficiency (GHD). Because Insulin-like Growth Factor-I (IGF-I) plays a pivotal role, GHD could also be considered as a form of IGF-I deficiency (IGFD). Although IGFD can develop at any level of the GH-releasing hormone (GHRH)-GH-IGF axis, a differe ...[more]