Rodletless mutants of Aspergillus fumigatus.
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ABSTRACT:
SUBMITTER: Thau N
PROVIDER: S-EPMC303120 | biostudies-other | 1994 Oct
REPOSITORIES: biostudies-other
Publications
rodletless mutants of Aspergillus fumigatus.
Thau N N Monod M M Crestani B B Rolland C C Tronchin G G Latgé J P JP Paris S S
Infection and immunity 19941001 10
Conidia of Aspergillus fumigatus adhere in vitro to host proteins and cells via the outer cell wall layer. The rodA gene of A. fumigatus was cloned by homology with the rodA gene of Aspergillus nidulans, which is involved in the structure of the rodlets characteristic of the surface layer. The A. fumigatus RODA protein sequence has 85% similarity to that of A. nidulans RODA; the sequence codes for a hydrophobin, a low-molecular-weight protein moderately hydrophobic and rich in cysteines. The gen ...[more]
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