Ontology highlight
ABSTRACT:
SUBMITTER: Proenca CC
PROVIDER: S-EPMC3051006 | biostudies-other | 2011 Mar
REPOSITORIES: biostudies-other
Proenca Catia C CC Gao Kate P KP Shmelkov Sergey V SV Rafii Shahin S Lee Francis S FS
Trends in neurosciences 20110301 3
Slitrks are a family of structurally related transmembrane proteins belonging to the leucine-rich repeat (LRR) superfamily. Six family members exist (Slitrk1-6) and all are highly expressed in the central nervous system (CNS). Slitrks have been implicated in mediating basic neuronal processes, ranging from neurite outgrowth and dendritic elaboration to neuronal survival. Recent studies in humans and genetic mouse models have led to the identification of Slitrks as candidate genes that might be i ...[more]