Ontology highlight
ABSTRACT:
SUBMITTER: Chandra V
PROVIDER: S-EPMC3064852 | biostudies-other | 2011 Mar
REPOSITORIES: biostudies-other
Chandra Vinod V Ramakrishnan Rejimoan R Ramanathan Shalini S
Bioinformation 20110302 1
<h4>Unlabelled</h4>Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occurs approximately every 1000 bases in the overall human population. The non-synonymous SNPs (nsSNPs), lead to amino acid changes in the protein product may account for nearly half of the known genetic variations linked to inherited human diseases and cancer. One of the main problems of medical genetics today is to identify nsSNPs that underlie disease-related phenotypes in humans. An ...[more]