Ontology highlight
ABSTRACT:
SUBMITTER: Sineva EV
PROVIDER: S-EPMC3070315 | biostudies-other | 2010 Dec
REPOSITORIES: biostudies-other
Sineva Elena V EV Davydov Dmitri R DR
High pressure research 20101201 4
Living species inhabiting ocean deeps must adapt to high hydrostatic pressure. This adaptation, which must enable functioning under conditions of promoted protein hydration, is especially important for proteins such as cytochromes P450 that exhibit functionally important hydration-dehydration dynamics. Here we study the interactions of substrates with cytochrome P450-SS9, a putative fatty acid hydroxylase from the piezophilic bacterium Photobacterium profundum SS9, and characterize the protein's ...[more]