Ontology highlight
ABSTRACT:
SUBMITTER: Jenny A
PROVIDER: S-EPMC307085 | biostudies-other | 1995 Jul
REPOSITORIES: biostudies-other
Nucleic acids research 19950701 14
3'-processing of mRNA precursors depends on several protein factors. One of them, cleavage and polyadenylation specificity factor (CPSF) is required for the cleavage of the mRNA precursor or as well as for the tail elongation reaction. We have obtained complementary DNA encoding the 160 kDa subunit, which had previously been shown to interact with the AAUAAA polyadenylation signal. The cDNAs code for an open reading frame of 1444 amino acids. The translated protein has a calculated molecular wei ...[more]