Ontology highlight
ABSTRACT:
SUBMITTER: Hoshijima K
PROVIDER: S-EPMC307222 | biostudies-other | 1995 Sep
REPOSITORIES: biostudies-other
Hoshijima K K Kohyama A A Watakabe I I Inoue K K Sakamoto H H Shimura Y Y
Nucleic acids research 19950901 17
Somatic sex determination in Drosophila depends on the expression of Sex-lethal (Sxl), whose level is determined by the relative number of X chromosomes and sets of autosomes (X:A ratio). The first step in regulation of Sxl expression is transcriptional control from its early promoter and several genes encoding transcription factors of the helix-loop-helix (HLH) family such as daughterless (da), sisterless-b (sis-b), deadpan (dpn) and extramacrochaetae (emc) have been implicated. By the use of t ...[more]