Ontology highlight
ABSTRACT:
SUBMITTER: Cheng TW
PROVIDER: S-EPMC3073606 | biostudies-other | 2010 Dec
REPOSITORIES: biostudies-other
Cheng Ting-Wen TW Liu Xiao-Bo XB Faulkner Regina L RL Stephan Alexander H AH Barres Ben A BA Huberman Andrew D AD Cheng Hwai-Jong HJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 20101201 48
Throughout the nervous system, neurons restrict their connections to specific depths or "layers" of their targets to constrain the type and number of synapses they make. Despite the importance of lamina-specific synaptic connectivity, the mechanisms that give rise to this feature in mammals remain poorly understood. Here we examined the cellular events underlying the formation of lamina-specific retinal ganglion cell (RGC) axonal projections to the superior colliculus (SC) of the mouse. By combi ...[more]