Effect of site-specific modification on restriction endonucleases and DNA modification methyltransferases.
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ABSTRACT:
SUBMITTER: McClelland M
PROVIDER: S-EPMC308336 | biostudies-other | 1994 Sep
REPOSITORIES: biostudies-other
Publications
Effect of site-specific modification on restriction endonucleases and DNA modification methyltransferases.
McClelland M M Nelson M M Raschke E E
Nucleic acids research 19940901 17
Restriction endonucleases have site-specific interactions with DNA that can often be inhibited by site-specific DNA methylation and other site-specific DNA modifications. However, such inhibition cannot generally be predicted. The empirically acquired data on these effects are tabulated for over 320 restriction endonucleases. In addition, a table of known site-specific DNA modification methyltransferases and their specificities is presented along with EMBL database accession numbers for cloned g ...[more]
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