Ontology highlight
ABSTRACT:
SUBMITTER: Kabaso D
PROVIDER: S-EPMC3088653 | biostudies-other | 2011 May
REPOSITORIES: biostudies-other
Kabaso Doron D Shlomovitz Roie R Schloen Kathrin K Stradal Theresia T Gov Nir S NS
PLoS computational biology 20110505 5
The forces that arise from the actin cytoskeleton play a crucial role in determining the cell shape. These include protrusive forces due to actin polymerization and adhesion to the external matrix. We present here a theoretical model for the cellular shapes resulting from the feedback between the membrane shape and the forces acting on the membrane, mediated by curvature-sensitive membrane complexes of a convex shape. In previous theoretical studies we have investigated the regimes of linear ins ...[more]