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Redetermined structure, inter-molecular inter-actions and absolute configuration of royleanone.

ABSTRACT: The structure of the title diterpenoid, C(20)H(28)O(3), {systematic name: (4bS,8aS)-3-hy-droxy-2-isopropyl-4b,8,8-trimethyl-4b,5,6,7,8,8a,9,10-octa-hydro-phenanthrene-1,4-dione} is confirmed [Eugster et al. (1993 ?). Private communication (refcode HACGUN). CCDC, Union Road, Cambridge] and its packing is now described. Its absolute structure was established by refinement against data collected with Cu radiation: the two stereogenic centres both have S configurations. One cyclo-hexane ring adopts a chair conformation whereas the other cyclo-hexane ring is in a half-chair conformation and the benzoquinone ring is slightly twisted. An intra-molecular O-H?O hydrogen bond generates an S(5) ring motif. In the crystal, mol-ecules are linked into chains along [010] by O-H?O hydrogen bonds and weak C-H?O inter-actions. The packing also features C?O [3.131?(3)?Å] short contacts.

SUBMITTER: Fun HK

PROVIDER: S-EPMC3089143 | biostudies-other | 2011 May

REPOSITORIES: biostudies-other

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Redetermined structure, inter-molecular inter-actions and absolute configuration of royleanone.

Fun Hoong-Kun HK Chantrapromma Suchada S Salae Abdul Wahab AW Razak Ibrahim Abdul IA Karalai Chatchanok C

Acta crystallographica. Section E, Structure reports online 20110407 Pt 5

The structure of the title diterpenoid, C(20)H(28)O(3), {systematic name: (4bS,8aS)-3-hy-droxy-2-isopropyl-4b,8,8-trimethyl-4b,5,6,7,8,8a,9,10-octa-hydro-phenanthrene-1,4-dione} is confirmed [Eugster et al. (1993 ▶). Private communication (refcode HACGUN). CCDC, Union Road, Cambridge] and its packing is now described. Its absolute structure was established by refinement against data collected with Cu radiation: the two stereogenic centres both have S configurations. One cyclo-hexane ring adopts ...[more]

PMID: 21754362

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