Ontology highlight
ABSTRACT:
SUBMITTER: White JH
PROVIDER: S-EPMC309859 | biostudies-other | 1993 Aug
REPOSITORIES: biostudies-other
Nucleic acids research 19930801 16
The gene encoding DNA polymerase alpha from the human malaria parasite Plasmodium falciparum has been sequenced and characterised. The deduced amino acid sequence possesses the seven sequence motifs which characterise eukaryotic replicative DNA polymerases (I-VII) and four of five motifs (A-E) identified in alpha DNA polymerases. The predicted protein also contains sequences which are reminiscent of Plasmodium proteins but absent from other DNA polymerases. These include four blocks of additiona ...[more]