Ontology highlight
ABSTRACT:
SUBMITTER: Ng SS
PROVIDER: S-EPMC3101080 | biostudies-other | 2011 May
REPOSITORIES: biostudies-other
FEBS letters 20110407 9
We investigated mRNA expression of 49 nuclear hormone receptors (NRs) and 35 transcriptional coregulators in mouse bone marrow-derived dendritic cells (DCs) upon infection with Newcastle Disease virus (NDV) or murine cytomegalovirus (MCMV). These viruses regulated mRNA expression of some NRs among which NOR1 and LXRα were highly induced at mRNA and protein levels. Exogenous expression of the latter NRs repressed IRF3- or IRF7-induced transactivation of the interferon β promoter and NDV infection ...[more]