Caveolae and lipid trafficking in adipocytes.
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ABSTRACT:
SUBMITTER: Pilch PF
PROVIDER: S-EPMC3103140 | biostudies-other | 2011
REPOSITORIES: biostudies-other
Publications
Caveolae and lipid trafficking in adipocytes.
Pilch Paul F PF Meshulam Tova T Ding Shiying S Liu Libin L
Clinical lipidology 20110101 1
The abundance of caveolae in adipocytes suggests a possible cell-specific role for these structures, and because these cells take up and release fatty acids as their quantitatively most robust activity, modulation of fatty acid movement is one such role that is supported by substantial in vitro and in vivo data. In addition, caveolae are particularly rich in cholesterol and sphingolipids, and indeed, fat cells harbor more cholesterol than any other tissue. In this article, we review the role of ...[more]
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