Ontology highlight
ABSTRACT:
SUBMITTER: Mitchell DL
PROVIDER: S-EPMC310358 | biostudies-other | 1992 Jan
REPOSITORIES: biostudies-other
Mitchell D L DL Jen J J Cleaver J E JE
Nucleic acids research 19920101 2
Cyclobutane pyrimidine dimers were quantified at the sequence level after irradiation with solar ultraviolet (UVB) and nonsolar ultraviolet (UVC) light sources. The yield of photoproducts at specific sites was dependent on the nucleotide composition in and around the potential lesion as well as on the wavelength of ultraviolet light used to induce the damage. Induction was greater in the presence of 5' flanking pyrimidines than purines; 5' guanine inhibited induction more than adenine. UVB irrad ...[more]