Ontology highlight
ABSTRACT:
SUBMITTER: Moran CL
PROVIDER: S-EPMC3105467 | biostudies-other | 2011 Jun
REPOSITORIES: biostudies-other
Moran Cindy L CL Le Vi-Huyen VH Chimalakonda Krishna C KC Smedley Amy L AL Lackey Felisia D FD Owen Suzanne N SN Kennedy Paul D PD Endres Gregory W GW Ciske Fred L FL Kramer James B JB Kornilov Andrei M AM Bratton L D LD Dobrowolski Paul J PJ Wessinger William D WD Fantegrossi William E WE Prather Paul L PL James Laura P LP Radominska-Pandya Anna A Moran Jeffery H JH
Analytical chemistry 20110506 11
"K2/SPICE" products are commonly laced with aminoalkylindole synthetic cannabinoids (i.e., JWH-018 and JWH-073) and are touted as "legal" marijuana substitutes. Here we validate a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for measuring urinary concentrations of JWH-018, JWH-073, and several potential metabolites of each. The analytical procedure has high capacity for sample throughput and does not require solid phase or liquid extraction. Evaluation of human urine specimen ...[more]