Ontology highlight
ABSTRACT:
SUBMITTER: Hellmann JK
PROVIDER: S-EPMC3116815 | biostudies-other | 2011 Jun
REPOSITORIES: biostudies-other
Hellmann Janina Kristin JK Münter Sylvia S Kudryashev Mikhail M Schulz Simon S Heiss Kirsten K Müller Ann-Kristin AK Matuschewski Kai K Spatz Joachim P JP Schwarz Ulrich S US Frischknecht Friedrich F
PLoS pathogens 20110616 6
Migrating cells are guided in complex environments mainly by chemotaxis or structural cues presented by the surrounding tissue. During transmission of malaria, parasite motility in the skin is important for Plasmodium sporozoites to reach the blood circulation. Here we show that sporozoite migration varies in different skin environments the parasite encounters at the arbitrary sites of the mosquito bite. In order to systematically examine how sporozoite migration depends on the structure of the ...[more]