Dataset Information

Coarse to fine dynamics of monocular and binocular processing in human pattern vision.

ABSTRACT: Biological image processing has been hypothesized to adopt a coarse to fine strategy: the image is initially analyzed at a coarse spatial scale, and this analysis is then used to guide subsequent inspection at a finer scale. Neurons in visual cortex often display response characteristics that are consistent with this hypothesis for both monocular and binocular signals. Puzzlingly, measurements in human observers have failed to expose similar coarse to fine dynamics for human pattern vision, questioning the applicability of direct parallels between single neurons and perception. We performed a series of measurements using experimental protocols that were specifically designed to examine this question in more detail. We were able to confirm that, when the analysis is restricted to the linear properties of the perceptual process, no coarse to fine dynamics were evident in the data. However, when the analysis was extended to nonlinear descriptors, a clear coarse to fine structure emerged that consisted of two processes: an early nonlinear process operating on a coarse spatial scale followed by a linear process operating on a fine spatial scale. These results potentially serve to reduce the gap between the electrophysiological and behavioral findings.

SUBMITTER: Neri P

PROVIDER: S-EPMC3127878 | biostudies-other | 2011 Jun

REPOSITORIES: biostudies-other

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Coarse to fine dynamics of monocular and binocular processing in human pattern vision.

Neri Peter P

Proceedings of the National Academy of Sciences of the United States of America 20110613 26

Biological image processing has been hypothesized to adopt a coarse to fine strategy: the image is initially analyzed at a coarse spatial scale, and this analysis is then used to guide subsequent inspection at a finer scale. Neurons in visual cortex often display response characteristics that are consistent with this hypothesis for both monocular and binocular signals. Puzzlingly, measurements in human observers have failed to expose similar coarse to fine dynamics for human pattern vision, ques ...[more]

PMID: 21670301

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Project description:Although the association between visual acuity (VA) and vision-related quality of life (VRQoL) has been well reported in patients with type 2 diabetes mellitus (T2DM), little is known about how unilateral and bilateral VA affects daily performance in such patients. For this cross-sectional study, patients were recruited from the Diabetes Shared Care Network of the Division of Endocrinology and Metabolism, Zhong-Xiao Branch, Taipei City Hospital in Taiwan. Ninety patients with T2DM (51 men and 39 women) with a mean age of 60.3 ± 10.5 (standard deviation) years, 47% of whom had diabetic retinopathy, were included. The purposes were to compare the impacts of VA in the better eye, both eyes, and three forms of functional acuity scores (FAS) on VRQoL in patients with T2DM. VRQoL and corrected VA were assessed with the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) and Early Treatment Diabetic Retinopathy Study (ETDRS) chart, respectively. Three FAS algorithms proposed by Colenbrander and the American Medical Association were used to assess FAS. Regression analyses were performed to determine the correlations among the five types of VA, the original composite scores, and the Rasch-calibrated composite scores of the NEI VFQ-25 on all patients with T2DM and on the same patients stratified by diabetic retinopathy (DR) and no-DR. The VA of both eyes had a higher impact on VRQoL and revealed a lower reduction estimated by the two forms of composite scores than did the VA of the better eye and three FAS algorithms (compared with binocular VA β estimates, - 14.5%, - 15.8%, - 29.3%, and - 11.8% for original composite scores, and - 16.1%, - 14.0%, - 24.6%, and 10.3% for Rasch-calibrated composite scores). When the T2DM group was stratified into DR and no-DR groups, significant associations between VA and VRQoL were observed only in the DR group. The VA of both eyes also had the greatest impact and reduction after stratification. The results indicated that unilateral better-eye VA and VA estimated by the three FAS algorithms seems to underestimate the impact of visual impairment on self-report VRQoL in patients with T2DM. This study provides empirical support for the importance of binocular VA assessment in regular clinical diabetes eye care.

Dataset Information

Coarse to fine dynamics of monocular and binocular processing in human pattern vision.

Publications

Coarse to fine dynamics of monocular and binocular processing in human pattern vision.

Similar Datasets

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