Adjuvant Bisphosphonate Therapy in Postmenopausal Breast Cancer Patients.
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ABSTRACT:
SUBMITTER: Gnant M
PROVIDER: S-EPMC3132953 | biostudies-other | 2010
REPOSITORIES: biostudies-other
Publications
Adjuvant Bisphosphonate Therapy in Postmenopausal Breast Cancer Patients.
Breast care (Basel, Switzerland) 20101029 5
Adjuvant bisphosphonate therapy is increasingly used in postmenopausal breast cancer patients. This is based on level-one evidence that bisphosphonates, particularly zoledronic acid, can effectively prevent cancer treatment-induced bone loss in breast cancer patients receiving estradiol-lowering endocrine therapies such as aromatase inhibitors. Furthermore, emerging data from large clinical trials suggest that additional anticancer benefits can be derived due to a positive impact on the bone mar ...[more]
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