RNA-based gene therapy for the treatment and prevention of HIV: from bench to bedside.
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ABSTRACT:
SUBMITTER: Zeller SJ
PROVIDER: S-EPMC3178861 | biostudies-other | 2011 Sep
REPOSITORIES: biostudies-other
Publications
RNA-based gene therapy for the treatment and prevention of HIV: from bench to bedside.
Zeller Skye J SJ Kumar Priti P
The Yale journal of biology and medicine 20110901 3
Gene therapy is considered a feasible approach for the treatment and prevention of HIV/AIDS. Targeting both viral genes and host dependency factors can interfere with the viral lifecycle and prevent viral replication. A number of approaches have been taken to target these genes, including ribozymes, aptamers, and RNAi based therapies. A number of these therapies are now beginning to make their way into clinical trials and providing proof of principle that gene therapy is a safe and realistic opt ...[more]
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