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Controversies in the adjuvant therapy of endometrial cancer.


ABSTRACT: Endometrial cancer is the most common malignancy of the female genital tract. Surgical treatment includes hysterectomy, bilateral salpingo-oophorectomy, and an appropriate staging procedure. Relapse of endometrial cancer may occur in patients with high risk factors, such as old age, grade 3 cancer, deep myometrial invasion, and papillary serous and clear cell types. In recent years, several randomized trials reported the results of adjuvant therapy for patients with high risk factors. Nonetheless, some controversies still exist. This paper presents and discusses the results of important randomized trials of adjuvant therapy for endometrial cancer with risk factors.

SUBMITTER: Hsiao SM 

PROVIDER: S-EPMC3182372 | biostudies-other | 2011

REPOSITORIES: biostudies-other

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Controversies in the adjuvant therapy of endometrial cancer.

Hsiao Sheng-Mou SM   Wei Lin-Hung LH  

ISRN obstetrics and gynecology 20110929


Endometrial cancer is the most common malignancy of the female genital tract. Surgical treatment includes hysterectomy, bilateral salpingo-oophorectomy, and an appropriate staging procedure. Relapse of endometrial cancer may occur in patients with high risk factors, such as old age, grade 3 cancer, deep myometrial invasion, and papillary serous and clear cell types. In recent years, several randomized trials reported the results of adjuvant therapy for patients with high risk factors. Nonetheles  ...[more]

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