Atomic force microscopy of electrospun organic-inorganic lipid nanofibers.
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ABSTRACT: An organic-inorganic hybridization strategy has been proposed to synthesize polymerizable lipid-based materials for the creation of highly stable lipid-mimetic nanostructures. We employ atomic force microscopy (AFM) to analyze the surface morphology and mechanical property of electrospun cholesteryl-succinyl silane (CSS) nanofibers. The AFM nanoindentation of the CSS nanofibers reveals elastic moduli of 55.3 ± 27.6 to 70.8 ± 35 MPa, which is significantly higher than the moduli of natural phospholipids and cholesterols. The study shows that organic-inorganic hybridization is useful in the design of highly stable lipid-based materials.
SUBMITTER: Zhang J
PROVIDER: S-EPMC3189251 | biostudies-other | 2011 Sep
REPOSITORIES: biostudies-other
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