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4'-[5-(4-Fluoro-phen-yl)pyridin-3-yl]-1'-methyl-dispiro-[indan-2,2'-pyrrolidine-3',2''-indan]-1,3,1''-trione.

ABSTRACT: In the title compound, C(32)H(23)FN(2)O(3), the pyrrolidine ring adopts an envelope conformation. The monoketo- and diketo-substituted five-membered rings are in envelope and half-chair conformations, respectively. The mol-ecular structure is stabilized by an intra-molecular C-H?O hydrogen bond, which generates an S(6) ring motif. In the crystal, mol-ecules are linked via inter-molecular C-H?N and C-H?O hydrogen bonds into a three-dimensional network. The crystal structure is further consolidated by C-H?? inter-actions.

SUBMITTER: Wei AC

PROVIDER: S-EPMC3200886 | biostudies-other | 2011 Sep

REPOSITORIES: biostudies-other

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4'-[5-(4-Fluoro-phen-yl)pyridin-3-yl]-1'-methyl-dispiro-[indan-2,2'-pyrrolidine-3',2''-indan]-1,3,1''-trione.

Wei Ang Chee AC Ali Mohamed Ashraf MA Ismail Rusli R Quah Ching Kheng CK Fun Hoong-Kun HK

Acta crystallographica. Section E, Structure reports online 20110827 Pt 9

In the title compound, C(32)H(23)FN(2)O(3), the pyrrolidine ring adopts an envelope conformation. The monoketo- and diketo-substituted five-membered rings are in envelope and half-chair conformations, respectively. The mol-ecular structure is stabilized by an intra-molecular C-H⋯O hydrogen bond, which generates an S(6) ring motif. In the crystal, mol-ecules are linked via inter-molecular C-H⋯N and C-H⋯O hydrogen bonds into a three-dimensional network. The crystal structure is further consolidate ...[more]

PMID: 22058982

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