Ontology highlight
ABSTRACT:
SUBMITTER: Hassan A
PROVIDER: S-EPMC3225001 | biostudies-other | 2011 Sep
REPOSITORIES: biostudies-other
Hassan Abbas A Townsend Ian A IA Krische Michael J MJ
Chemical communications (Cambridge, England) 20110810 36
Methallyl chloride serves as an efficient allyl donor in highly enantioselective Grignard Nozaki-Hiyama methallylations from the alcohol or aldehyde oxidation level via iridium catalyzed transfer hydrogenation. Under identical conditions, methallyl acetate does not react efficiently. Double methallylation of 1,3-propanediol provides the C(2)-symmetric adduct as a single enantiomer, as determined by HPLC analysis. ...[more]