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4-(4-Methyl-piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro-meth-yl)quinoline.

ABSTRACT: In the title compound, C(23)H(20)F(3)N(5)O, the piperazine ring adopts a chair conformation. The quinoline ring makes dihedral angles of 56.61?(11), 49.94?(12) and 42.58?(14)° with the piperazine ring, the 1,3,4-oxadiazole ring and the benzene ring, respectively. An intra-molecular C-H?O hydrogen bond generates an S(7) ring motif. In the crystal, mol-ecules are linked into infinite chains along the b axis by C-H?N hydrogen bonds.

SUBMITTER: Fun HK

PROVIDER: S-EPMC3247502 | biostudies-other | 2011 Nov

REPOSITORIES: biostudies-other

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4-(4-Methyl-piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro-meth-yl)quinoline.

Fun Hoong-Kun HK Arshad Suhana S Garudachari B B Isloor Arun M AM Satyanarayan M N MN

Acta crystallographica. Section E, Structure reports online 20111029 Pt 11

In the title compound, C(23)H(20)F(3)N(5)O, the piperazine ring adopts a chair conformation. The quinoline ring makes dihedral angles of 56.61 (11), 49.94 (12) and 42.58 (14)° with the piperazine ring, the 1,3,4-oxadiazole ring and the benzene ring, respectively. An intra-molecular C-H⋯O hydrogen bond generates an S(7) ring motif. In the crystal, mol-ecules are linked into infinite chains along the b axis by C-H⋯N hydrogen bonds. ...[more]

PMID: 22220120

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