Ontology highlight
ABSTRACT:
SUBMITTER: Jackson IJ
PROVIDER: S-EPMC328466 | biostudies-other | 1991 Jul
REPOSITORIES: biostudies-other
Jackson I J IJ Chambers D M DM Budd P S PS Johnson R R
Nucleic acids research 19910701 14
We have determined the exon structure of the mouse tyrosinase-related protein-1 (TRP-1) gene. The gene is only 15kb in length, but contains seven introns, in contrast to the tyrosinase gene which is almost 100kb long with only four introns. Only two introns are located in homologous positions in both genes. Intron I of TRP-1 has three alternative 5' splice sites clustered within 21bp, which all splice to the same 3' site. Intron V has a very unusual 5' splice site, which has the dinucleotide GC ...[more]