Ontology highlight
ABSTRACT:
SUBMITTER: Aksoy S
PROVIDER: S-EPMC330328 | biostudies-other | 1990 Feb
REPOSITORIES: biostudies-other
Nucleic acids research 19900201 4
We have characterized a retrotransposon in Trypanosoma brucei gambiense uniquely associated with the spliced-leader (SL) RNA gene cluster (Spliced Leader Associated Conserved Sequence, SLACS). There are nine copies of SLACS and DNA sequence analysis of one shows the hallmarks of Line-1 like elements. SLACS has generated a 49 bp target DNA duplication at its insertion site and its 3'-end is preceded by a poly(A) stretch. Two putative open reading frames (ORFs) span 75% of the element. ORF1 has Cy ...[more]