Ontology highlight
ABSTRACT:
SUBMITTER: Wilke SA
PROVIDER: S-EPMC3310804 | biostudies-other | 2012 Feb
REPOSITORIES: biostudies-other
Wilke Scott A SA Hall Benjamin J BJ Antonios Joseph K JK Denardo Laura A LA Otto Stefanie S Yuan Bo B Chen Fading F Robbins Elissa M EM Tiglio Katie K Williams Megan E ME Qiu Zilong Z Biederer Thomas T Ghosh Anirvan A
Neural development 20120227
<h4>Background</h4>The assembly of neural circuits requires the concerted action of both genetically determined and activity-dependent mechanisms. Calcium-regulated transcription may link these processes, but the influence of specific transcription factors on the differentiation of synapse-specific properties is poorly understood. Here we characterize the influence of NeuroD2, a calcium-dependent transcription factor, in regulating the structural and functional maturation of the hippocampal moss ...[more]