Ontology highlight
ABSTRACT:
SUBMITTER: Liu IC
PROVIDER: S-EPMC3315813 | biostudies-other | 2012 Apr
REPOSITORIES: biostudies-other
Liu I-Chun IC Chiu Sheng-Wen SW Lee Hsin-Yi HY Leu Jun-Yi JY
Molecular biology of the cell 20120215 7
One of many physiological adjustments in quiescent cells is spatial regulation of specific proteins and RNA important for the entry to or exit from the stationary phase. By examining the localization of epigenetic-related proteins in Saccharomyces cerevisiae, we observed the formation of a reversible cytosolic "stationary-phase granule" (SPG) by Hos2, a nuclear histone deacetylase. In the stationary phase, hos2 mutants display reduced viability. Additionally, they exhibit a significant delay whe ...[more]