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Renal cell carcinoma with secondary hemophagocytic syndrome: A case report.


ABSTRACT: A patient with a suspected malignancy and pancytopenia warrants much consideration. Most clinicians would consider bone marrow infiltrative process, heralding a grave prognosis. However, rare occurrence of hemophagocytic lymphohistiocytosis is another diagnostic possibility we should keep in mind. The treatment choices and overall prognosis may differ from patients without hemophagocytosis. We present a case of incidentally found advanced renal cell carcinoma (RCC) concurrent with hemophagocytosis process in the bone marrow. We also discuss the importance of this finding.

SUBMITTER: Chao CT 

PROVIDER: S-EPMC3328575 | biostudies-other | 2012 Apr

REPOSITORIES: biostudies-other

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Renal cell carcinoma with secondary hemophagocytic syndrome: A case report.

Chao Chia-Ter CT   Kao Chih-Chin CC   Lee Szu-Ying SY   Ho Shu-Jung SJ   Jhuang Ying-Jheng YJ   Li Lars Hung-Yuan LH   Kao Tze-Wah TW  

Canadian Urological Association journal = Journal de l'Association des urologues du Canada 20120401 2


A patient with a suspected malignancy and pancytopenia warrants much consideration. Most clinicians would consider bone marrow infiltrative process, heralding a grave prognosis. However, rare occurrence of hemophagocytic lymphohistiocytosis is another diagnostic possibility we should keep in mind. The treatment choices and overall prognosis may differ from patients without hemophagocytosis. We present a case of incidentally found advanced renal cell carcinoma (RCC) concurrent with hemophagocytos  ...[more]

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