Ontology highlight
ABSTRACT:
SUBMITTER: Page JP
PROVIDER: S-EPMC3329589 | biostudies-other | 2012 Apr
REPOSITORIES: biostudies-other
Page Jordan P JP RajanBabu T V TV
Journal of the American Chemical Society 20120330 15
1-Vinylcycloalkenes undergo highly regio- and enantioselective (>98% ee) 1,4-hydrovinylation (HV) when treated with ethylene (1 atm) at room temperature in the presence of [(S,S)-2,4-bis-diphenylphosphinopentane (BDPP)]CoCl(2) (0.05 equiv) and methylaluminoxane. The minor 1,2-HV products, seen only in 1-vinylcyclohexene (~15%) and 1-vinylcycloheptene (2%), are formed as racemic mixtures. The corresponding Ni(II)-catalyzed HV reactions of these substrates give mostly the 1,2-adducts. Racemic 4-te ...[more]