Monte Carlo simulation of the Spearman-Kaerber TCID50.
Ontology highlight
ABSTRACT:
SUBMITTER: Wulff NH
PROVIDER: S-EPMC3331834 | biostudies-other | 2012
REPOSITORIES: biostudies-other
Publications
Monte Carlo simulation of the Spearman-Kaerber TCID50.
Wulff Niels H NH Tzatzaris Maria M Young Philip J PJ
Journal of clinical bioinformatics 20120213 1
<h4>Background</h4>In the biological sciences the TCID50 (median tissue culture infective dose) assay is often used to determine the strength of a virus.<h4>Methods</h4>When the so-called Spearman-Kaerber calculation is used, the ratio between the pfu (the number of plaque forming units, the effective number of virus particles) and the TCID50, theoretically approaches a simple function of Eulers constant. Further, the standard deviation of the logarithm of the TCID50 approaches a simple function ...[more]
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