Unknown

Dataset Information

0

Multilayer DNA origami packed on hexagonal and hybrid lattices.


ABSTRACT: "Scaffolded DNA origami" has been proven to be a powerful and efficient approach to construct two-dimensional or three-dimensional objects with great complexity. Multilayer DNA origami has been demonstrated with helices packing along either honeycomb-lattice geometry or square-lattice geometry. Here we report successful folding of multilayer DNA origami with helices arranged on a close-packed hexagonal lattice. This arrangement yields a higher density of helical packing and therefore higher resolution of spatial addressing than has been shown previously. We also demonstrate hybrid multilayer DNA origami with honeycomb-lattice, square-lattice, and hexagonal-lattice packing of helices all in one design. The availability of hexagonal close-packing of helices extends our ability to build complex structures using DNA nanotechnology.

SUBMITTER: Ke Y 

PROVIDER: S-EPMC3336742 | biostudies-other | 2012 Jan

REPOSITORIES: biostudies-other

altmetric image

Publications

Multilayer DNA origami packed on hexagonal and hybrid lattices.

Ke Yonggang Y   Voigt Niels V NV   Gothelf Kurt V KV   Shih William M WM  

Journal of the American Chemical Society 20120113 3


"Scaffolded DNA origami" has been proven to be a powerful and efficient approach to construct two-dimensional or three-dimensional objects with great complexity. Multilayer DNA origami has been demonstrated with helices packing along either honeycomb-lattice geometry or square-lattice geometry. Here we report successful folding of multilayer DNA origami with helices arranged on a close-packed hexagonal lattice. This arrangement yields a higher density of helical packing and therefore higher reso  ...[more]

Similar Datasets

| S-EPMC2821935 | biostudies-literature
| S-EPMC8694312 | biostudies-literature
| S-EPMC5710187 | biostudies-literature
| S-EPMC8276786 | biostudies-literature
| S-EPMC4593175 | biostudies-other
| S-EPMC6232174 | biostudies-literature
| S-EPMC7235251 | biostudies-literature
| S-EPMC5187439 | biostudies-other
| S-EPMC3957201 | biostudies-literature
| S-EPMC6310857 | biostudies-literature