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Dabigatran for stroke prevention in nonvalvular atrial fibrillation: answers to challenging "real-world" questions.


ABSTRACT: Dabigatran etexilate is a novel, oral, reversible, direct thrombin inhibitor that constitutes a major breakthrough for stroke prevention in patients with nonvalvular atrial fibrillation (AF). Dabigatran was the first new oral anticoagulant approved in Europe and became available in Portugal, for stroke prevention in nonvalvular AF, earlier than in most European countries. This paper is the joint effort of a panel of experts from different specialties and provides information on the use of dabigatran, in anticipation of the challenges that will come with increased usage.

SUBMITTER: Ferreira J 

PROVIDER: S-EPMC3356980 | biostudies-other | 2012

REPOSITORIES: biostudies-other

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Dabigatran for stroke prevention in nonvalvular atrial fibrillation: answers to challenging "real-world" questions.

Ferreira Jorge J   Ferreira Daniel D   Viana-Baptista Miguel M   Bettencourt Paulo P   Cernadas Rui R   Crespo Francisco F  

Thrombosis 20120507


Dabigatran etexilate is a novel, oral, reversible, direct thrombin inhibitor that constitutes a major breakthrough for stroke prevention in patients with nonvalvular atrial fibrillation (AF). Dabigatran was the first new oral anticoagulant approved in Europe and became available in Portugal, for stroke prevention in nonvalvular AF, earlier than in most European countries. This paper is the joint effort of a panel of experts from different specialties and provides information on the use of dabiga  ...[more]

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