Ontology highlight
ABSTRACT:
SUBMITTER: Dubin MJ
PROVIDER: S-EPMC3361582 | biostudies-other | 2012 Mar
REPOSITORIES: biostudies-other
Dubin Marc J MJ Weissman Myrna M MM Xu Dongrong D Bansal Ravi R Hao Xuejun X Liu Jun J Warner Virginia V Peterson Bradley S BS
Psychiatry research 20120301 3
Frontal and parietal lesions may cause depression, and cortical thinning of the right frontal and parietal lobes has been shown to be a marker of risk for familial major depression. We studied biological offspring within a three-generation cohort, in which risk was defined by the depression status of the first generation, to identify regional volume differences associated with risk for depression throughout the cerebrum. We found reduced frontal and parietal white matter volumes in the high-risk ...[more]