Ontology highlight
ABSTRACT:
SUBMITTER: Shirley MD
PROVIDER: S-EPMC3370055 | biostudies-other | 2012 Jul
REPOSITORIES: biostudies-other
Shirley Matthew D MD Baugher Joseph D JD Stevens Eric L EL Tang Zhenya Z Gerry Norman N Beiswanger Christine M CM Berlin Dorit S DS Pevsner Jonathan J
Human mutation 20120416 7
Tens of thousands of lymphoblastoid cell lines (LCLs) have been established by the research community, providing nearly unlimited source material from samples of interest. LCLs are used to address questions in population genomics, mechanisms of disease, and pharmacogenomics. Thus, it is of fundamental importance to define the extent of chromosomal variation in LCLs. We measured variation in genotype and copy number in multiple LCLs derived from peripheral blood mononuclear cells (PBMCs) of singl ...[more]