2-Methyl-3-(2-methyl-phen-yl)-4-oxo-3,4-dihydro-quinazolin-8-yl 4-chloro-benzoate.

ABSTRACT: In the title compound, C(23)H(17)ClN(2)O(3), the quinazoline fused-ring system, including the ring-bound carbonyl-O and methyl-C atoms, is close to being planar (r.m.s. deviation = 0.044?Å) and is essentially orthogonal to both the 2-tolyl ring [dihedral angle = 89.51?(8)°] and to the ester group [the C-O-C-C torsion angle = -103.69?(16)°]. The carboxyl-ate group is almost coplanar with the benzene ring to which it is attached [O-C-C-C torsion angle = -4.7?(2)°]. The 2-tolyl ring system is disordered over two orientations in a 0.871?(3):0.129?(3) ratio. In the crystal, mol-ecules are consolidated into a three-dimensional architecture by C-H?Cl, C-H?O, C-H?N, C-H?? and ?-? inter-actions [inter-centroid distances = 3.6443?(9) and 3.8557?(11)?Å].

SUBMITTER: El-Azab AS 

PROVIDER: S-EPMC3393320 | biostudies-other | 2012 Jul

REPOSITORIES: biostudies-other