Ontology highlight
ABSTRACT:
SUBMITTER: Kotowski A
PROVIDER: S-EPMC3397600 | biostudies-other | 2011 Jun
REPOSITORIES: biostudies-other
Journal of gastrointestinal oncology 20110601 2
Pancreas cancer has a grave prognosis and treatment options remain limited despite advancement in anti-cancer chemotherapeutics. This review provides an overview of the emerging therapies for pancreas cancer, focusing on novel signal transduction inhibitors (insulin-like growth factor receptor, hedgehog/Smo, PI3k/Akt/mTOR) and cytotoxics (nab-paclitaxel) that are currently in clinical development. Despite the impact molecularly targeted agents have on other tumor types, their application without ...[more]